Poly (ADP-Ribose) Polymerase Mediates Diabetes-Induced Retinal Neuropathy

Retinal neuropathy is an early event in the development of diabetic retinopathy. One of the potential enzymes that are activated by oxidative stress in the diabetic retina is poly (ADP-ribose) polymerase (PARP). We investigated the effect of the PARP inhibitor 1,5-isoquinolinediol on the expression...

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Bibliographic Details
Main Authors: Ghulam Mohammad, Mohammad Mairaj Siddiquei, Ahmed M. Abu El-Asrar
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/510451