Safety and preliminary efficacy of orally administered lyophilized fecal microbiota product compared with frozen product given by enema for recurrent Clostridium difficile infection: A randomized clinical trial.

BACKGROUND:Fecal microbiota transplantation (FMT) via colonoscopy or enema has become a commonly used treatment of recurrent C. difficile infection (CDI). AIMS:To compare the safety and preliminary efficacy of orally administered lyophilized microbiota product compared with frozen product by enema....

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Main Authors: Zhi-Dong Jiang, Robert R Jenq, Nadim J Ajami, Joseph F Petrosino, Ashley A Alexander, Shi Ke, Tehseen Iqbal, Andrew W DuPont, Kenneth Muldrew, Yushu Shi, Christine Peterson, Kim-Anh Do, Herbert L DuPont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6214502?pdf=render