Non-Selective Cannabinoid Receptor Antagonists, Hinokiresinols Reduce Infiltration of Microglia/Macrophages into Ischemic Brain Lesions in Rat via Modulating 2-Arachidonolyglycerol-Induced Migration and Mitochondrial Activity.

Growing evidence suggests that therapeutic strategies to modulate the post-ischemic inflammatory responses are promising approaches to improve stroke outcome. Although the endocannabinoid system has been emerged as an endogenous therapeutic target to regulate inflammation after stroke insult, the do...

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Main Authors: Angela M A Anthony Jalin, Maheswari Rajasekaran, Paul L Prather, Jin Sun Kwon, Veeraswamy Gajulapati, Yongseok Choi, Chunsook Kim, Kisoo Pahk, Chung Ju, Won-Ki Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4627794?pdf=render