YM155 induces EGFR suppression in pancreatic cancer cells.

YM155 induces EGFR suppression in pancreatic cancer cells.

YM155, which inhibits the anti-apoptotic protein survivin, is known to exert anti-tumor effects in various cancers, including prostate and lung cancer. However, there are few reports describing the inhibitory effect of YM155 on human pancreatic cancers that highly express survivin. Here, we tested t...

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Bibliographic Details
Main Authors: Young-Soon Na, Soo-Jin Yang, Seung-Mi Kim, Kyung-Ah Jung, Jai-Hee Moon, Jae-Sik Shin, Dok Hyun Yoon, Yong Sang Hong, Min-Hee Ryu, Jae-Lyun Lee, Jung Shin Lee, Tae Won Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3377633?pdf=render

Internet

http://europepmc.org/articles/PMC3377633?pdf=render

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