Fast food diet-induced non-alcoholic fatty liver disease exerts early protective effect against acetaminophen intoxication in mice

Fast food diet-induced non-alcoholic fatty liver disease exerts early protective effect against acetaminophen intoxication in mice

Abstract Background Acetaminophen (APAP) is a readily available and safe painkiller. However, its overdose is the most common cause of acute liver injury (ALI). Many predisposing factors contribute to susceptibility to APAP-induced ALI. Non-alcoholic fatty liver disease (NAFLD), the major cause of c...

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Bibliographic Details
Main Authors: Tae Hyung Kim, Dahee Choi, Joo Young Kim, Jeong Hyeon Lee, Seung-Hoi Koo
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Gastroenterology
Subjects:
Acetaminophen
Non-alcoholic fatty liver disease
Drug-induced liver injury
Peroxisome proliferator-activated receptor gamma
Online Access:http://link.springer.com/article/10.1186/s12876-017-0680-z

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http://link.springer.com/article/10.1186/s12876-017-0680-z

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