Texture-based markers from structural imaging correlate with motor handicap in Parkinson’s disease

Abstract There is a growing need for surrogate biomarkers for Parkinson’s disease (PD). Structural analysis using magnetic resonance imaging with T1-weighted sequences has the potential to quantify histopathological changes. Degeneration is typically measured by the volume and shape of morphological...

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Bibliographic Details
Main Authors: Nacim Betrouni, Caroline Moreau, Anne-Sophie Rolland, Nicolas Carrière, Marie Chupin, Gregory Kuchcinski, Renaud Lopes, Romain Viard, Luc Defebvre, David Devos
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81209-4