Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease

Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease

Abstract Background Non-alcoholic fatty liver is one of the most common comorbidities of diabetes. It can cause disturbance of glucose and lipid metabolism in the body, gradually develop into liver fibrosis, and even cause liver cirrhosis. Mangiferin has a variety of pharmacological activities, espe...

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Bibliographic Details
Main Authors: He Lin, Houlei Teng, Wei Wu, Yong Li, Guangfu Lv, Xiaowei Huang, Wenhao Yan, Zhe Lin
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Pharmacology and Toxicology
Subjects:
Mangiferin calcium salt
Diabetes
NAFLD
Pharmacokinetics
Metabolomics
Bioavailability
Online Access:http://link.springer.com/article/10.1186/s40360-020-00438-x

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http://link.springer.com/article/10.1186/s40360-020-00438-x

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