Cyclical appearance of African trypanosomes in the cerebrospinal fluid: new insights in how trypanosomes enter the CNS.

It is textbook knowledge that human infective forms of Trypanosoma brucei, the causative agent of sleeping sickness, enter the brain across the blood-brain barrier after an initial phase of weeks (rhodesiense) or months (gambiense) in blood. Based on our results using an animal model, both statement...

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Bibliographic Details
Main Authors: Stefan Mogk, Andreas Meiwes, Swetlana Shtopel, Ulrich Schraermeyer, Michael Lazarus, Bruno Kubata, Hartwig Wolburg, Michael Duszenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24618708/?tool=EBI