Metformin attenuates carotid neointimal hyperplasia by modulating the vascular smooth muscle cell phenotype transformation through upregulation of TET2, Nur77 and calponin

Metformin is a drug used to treat type 2 diabetes based on its effectiveness as well as cardiovascular safety. Metformin has been shown to modulate proliferation and migration of vascular smooth muscle cells (VSMCs), but the underlying mechanisms of the effect of metformin on VSMC function remains u...

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Bibliographic Details
Main Authors: Lin Hao, Cheng Shuo, Yuan Zhichao, Yan Zhiqiang, Zhang Jifa
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2021-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100009L.pdf