Promoter-proximal pausing mediated by the exon junction complex regulates splicing
The exon junction complex (EJC) has been identified as functioning as a post-transcriptional gene regulator. Here the authors reveal that the complex also plays a part in the regulation of transcription by regulating the release of Pol II pausing into transcription elongation.
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-08381-0 |