Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates

Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates

Respiratory Syncytial Virus (RSV) is a leading cause of severe respiratory disease in infants and the elderly. No vaccine is presently available to address this major unmet medical need. We generated a new genetic vaccine based on chimpanzee Adenovirus (PanAd3-RSV) and Modified Vaccinia Ankara RSV (...

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Bibliographic Details
Main Authors: Angiolo Pierantoni, Maria Luisa Esposito, Virginia Ammendola, Federico Napolitano, Fabiana Grazioli, Adele Abbate, Mariarosaria del Sorbo, Loredana Siani, Anna Morena D'Alise, Alessandra Taglioni, Gemma Perretta, Antonio Siccardi, Elisa Soprana, Maddalena Panigada, Michelle Thom, Elisa Scarselli, Antonella Folgori, Stefano Colloca, Geraldine Taylor, Riccardo Cortese, Alfredo Nicosia, Stefania Capone, Alessandra Vitelli
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050116300304

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http://www.sciencedirect.com/science/article/pii/S2329050116300304

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