An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis

During mammalian embryogenesis, extensive cellular remodeling is needed for tissue morphogenesis. As effectors of cytoskeletal dynamics, Rho GTPases and their regulators are likely involved, but their daunting complexity has hindered progress in dissecting their functions. We overcome this hurdle by...

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Bibliographic Details
Main Authors: Melanie Laurin, Nicholas C Gomez, John Levorse, Ataman Sendoel, Megan Sribour, Elaine Fuchs
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/50226