Development and validation of a risk prediction model to diagnose Barrett's oesophagus (MARK-BE): a case-control machine learning approach

Summary: Background: Screening for Barrett's oesophagus relies on endoscopy, which is invasive and few who undergo the procedure are found to have the condition. We aimed to use machine learning techniques to develop and externally validate a simple risk prediction panel to screen individuals...

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Main Authors: Avi Rosenfeld, PhD, David G Graham, MBBS, Sarah Jevons, PhD, Jose Ariza, RGN, Daryl Hagan, MSc, Ash Wilson, BSc, Samuel J Lovat, Sarmed S Sami, MBBS, Omer F Ahmad, MBBS, Marco Novelli, ProfMBChB, Manuel Rodriguez Justo, MBBS, Alison Winstanley, MBBS, Eliyahu M Heifetz, PhD, Mordehy Ben-Zecharia, PhD, Uria Noiman, PhD, Rebecca C Fitzgerald, ProfMBChB, Peter Sasieni, ProfPhD, Laurence B Lovat, ProfMBBS, Karen Coker, Wanfeng Zhao, Kathryn Brown, Beverley Haynes, Tara Nuckcheddy Grant, Massimiliano di Pietro, Eleanor Dewhurst, Bincy Alias, Leanne Mills, Caroline Wilson, Elizabeth Bird-Lieberman, Jan Bornschein, Yean Lim, Kareem Shariff, Roberto Cayado Lopez, Myrna Udarbe, Claire Shaw, Glynis Rose, Ian Sargeant, M Al-Izzi, Roisin Schimmel, Elizabeth Green, Morgan Moorghen, Reshma Kanani, Mariann Baulf, Jayne Butcher, Adil Butt, Steve Bown, Gideon Lipman, Rami Sweis, Vinay Sehgal, Matthew Banks, Rehan Haidry, John Louis-Auguste, Darina Kohoutova, Sarah Kerr, Victor Eneh, Nigel Butter, Haroon Miah, Rommel Butawan, Grace Adesina, Sabrina Holohan, Joan Idris, Nick Hayes, Shajahan Wahed, Nelson Kath Houghton, Marc Hopton, Anne Eastick, Debasis Majumdar, Kassem Manuf, Lyndsey Fieldson, Helen Bailey, Jacobo Fernandez-Sordo Ortiz, Mina Patel, Suzanne Henry, Samantha Warburton, Jonathan White, Lisa Gadeke, Beverley Longhurst, Richmond Abeseabe, Peter Basford, Rupam Bhattacharyya, Scott Elliot, Roisin Bevan, Carly Brown, Philippa Laverick, Gayle Clifford, Anita Gibbons, Julie Ingmire, Abdullah Mawas, Jacquelyn Harvey, Sharon Cave
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:The Lancet: Digital Health
Online Access:http://www.sciencedirect.com/science/article/pii/S258975001930216X