Immunophenotypic Profiling of Erythroid Progenitor-Derived Extracellular Vesicles in Diamond-Blackfan Anaemia: A New Diagnostic Strategy.

Immunophenotypic Profiling of Erythroid Progenitor-Derived Extracellular Vesicles in Diamond-Blackfan Anaemia: A New Diagnostic Strategy.

Diamond-Blackfan Anaemia (DBA) is a rare inherited anaemia caused by heterozygous mutations in one of 13 ribosomal protein genes. Erythroid progenitors (BFU-E and CFU-E) in bone marrow (BM) show a proapoptotic phenotype. Suspicion of DBA is reached after exclusion of other forms of BM failure syndro...

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Bibliographic Details
Main Authors: Serena Macrì, Elisa Pavesi, Rossella Crescitelli, Anna Aspesi, Claudia Vizziello, Carlotta Botto, Paola Corti, Paola Quarello, Patrizia Notari, Ugo Ramenghi, Steven Robert Ellis, Irma Dianzani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0138200

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https://doi.org/10.1371/journal.pone.0138200

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