Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis.

Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis.

INTRODUCTION:Osteoarthritis (OA) is the most common degenerative joint disease and one of the major causes of disability worldwide. It is a multifactorial disorder with a significant genetic component. The heritability of OA has been estimated to be 60% for hip OA and 39% for knee OA. Genetic factor...

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Main Authors: Sini Skarp, Olli-Pekka Kämäräinen, Gong-Hong Wei, Eveliina Jakkula, Ilkka Kiviranta, Heikki Kröger, Juha Auvinen, Petri Lehenkari, Leena Ala-Kokko, Minna Männikkö
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6114922?pdf=render

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http://europepmc.org/articles/PMC6114922?pdf=render

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