HES6-1 and HES6-2 function through different mechanisms during neuronal differentiation.
Notch signalling plays a central role in the mechanisms regulating neuronal differentiation in the vertebrate nervous system. The transcriptional repressors encoded by Hes genes are the main effectors of this pathway, acting in neural progenitors during the lateral inhibition process to repress pron...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-12-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2996300?pdf=render |