Expression and subcellular localization of Discoidin Domain Receptor 1 (DDR1) define prostate cancer aggressiveness

Abstract Background The Discoidin Domain Receptor 1 (DDR1) is one of the two members of a unique family of receptor tyrosine kinase receptors that signal in response to collagen, which has been implicated in cancer progression. Here, we examined the expression of DDR1 in prostate cancer (PCa), and a...

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Bibliographic Details
Main Authors: R. Daniel Bonfil, Wei Chen, Semir Vranic, Anjum Sohail, Dongping Shi, Hyejeong Jang, Hyeong-Reh Kim, Marco Prunotto, Rafael Fridman
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-021-02206-1