CD4+CD45RA−FOXP3low Regulatory T Cells as Potential Biomarkers of Disease Activity in Systemic Lupus Erythematosus Brazilian Patients

CD4+CD45RA−FOXP3low Regulatory T Cells as Potential Biomarkers of Disease Activity in Systemic Lupus Erythematosus Brazilian Patients

Heren, we analyzed Treg cells as potential biomarkers of disease activity in systemic lupus erythematosus (SLE) patients. Peripheral blood mononuclear cells from 30 SLE patients (15 active: SLEDAI > 6/15 SLE remission: SLEDAI< 6) and 15 healthy volunteers were purified. Treg immunophenotyping...

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Main Authors: Helena L. Silva-Neta, Maria C. A. Brelaz-de-Castro, Mardonny B. O. Chagas, Henrique A. Mariz, Rodrigo G. de Arruda, Viviane F. de Vasconcelos, Michelly C. Pereira, Audrey Romano, Ivan R. Pitta, Claudia D. L. Marques, Angela L. B. P. Duarte, Moacyr J. B. M. Rêgo, Maira G. R. Pitta
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/3419565

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http://dx.doi.org/10.1155/2018/3419565

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