Increased uptake of α-hydroxy aldehyde-modified low density lipoprotein by macrophage scavenger receptors

Reactive aldehydes can be formed during the oxidation of lipids, glucose, and amino acids and during the nonenzymatic glycation of proteins. Low density lipoprotein (LDL) modified with malondialdehyde are taken up by scavenger receptors on macrophages. In the current studies we determined whether α-...

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Bibliographic Details
Main Authors: Mitsunobu Kawamura, Jay W. Heinecke, Alan Chait
Format: Article
Language:English
Published: Elsevier 2000-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320095