Diagnostic Screening Workflow for Mutations in the BRCA1 and BRCA2 Genes

Diagnostic Screening Workflow for Mutations in the BRCA1 and BRCA2 Genes

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Objectives: Screening for mutations in large genes is challenging in a molecular diagnostic environment. Sanger-based DNA sequencing methods are largely used; however, massively parallel sequencing (MPS) can accommodate increasing test demands and financial constraints. This study aimed to establish...

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Bibliographic Details
Main Authors: Stella Lai, Clare Brooke, Debra O. Prosser, Chuan-Ching Lan, Elaine Doherty, Donald R. Love
Format: Article
Language:English
Published: Sultan Qaboos University 2015-02-01
Series:Sultan Qaboos University Medical Journal
Subjects:
massively parallel sequencing
brca1 gene
brca2 gene
hboc syndrome
detection, heterozygote.
Online Access:https://journals.squ.edu.om/index.php/squmj/article/view/1989

Internet

https://journals.squ.edu.om/index.php/squmj/article/view/1989

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