A Survey on Tubulin and Arginine Methyltransferase Families Sheds Light on <i>P. lividus</i> Embryo as Model System for Antiproliferative Drug Development

A Survey on Tubulin and Arginine Methyltransferase Families Sheds Light on <i>P. lividus</i> Embryo as Model System for Antiproliferative Drug Development

Tubulins and microtubules (MTs) represent targets for taxane-based chemotherapy. To date, several lines of evidence suggest that effectiveness of compounds binding tubulin often relies on different post-translational modifications on tubulins. Among them, methylation was recently associated to drug...

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Bibliographic Details
Main Authors: Maria Antonietta Ragusa, Aldo Nicosia, Salvatore Costa, Caterina Casano, Fabrizio Gianguzza
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
tubulin
PRMT
post-translational modification
arginine methylation
sea urchin
echinoderms
Online Access:https://www.mdpi.com/1422-0067/20/9/2136

Internet

https://www.mdpi.com/1422-0067/20/9/2136

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