Efficacy of extended infusion of β-lactam antibiotics for the treatment of febrile neutropenia in haematologic patients: protocol for a randomised, multicentre, open-label, superiority clinical trial (BEATLE)

Efficacy of extended infusion of β-lactam antibiotics for the treatment of febrile neutropenia in haematologic patients: protocol for a randomised, multicentre, open-label, superiority clinical trial (BEATLE)

Abstract Background Febrile neutropaenia (FN) is a very common complication in patients with haematological malignancies and is associated with considerable morbidity and mortality. Broad-spectrum antipseudomonal β-lactam antibiotics (BLA) are routinely used for the treatment of cancer patients with...

Full description

Bibliographic Details
Main Authors: J. Laporte-Amargos, C. Gudiol, M. Arnan, P. Puerta-Alcalde, F. Carmona-Torre, M. Huguet, A. Albasanz-Puig, R. Parody, C. Garcia-Vidal, J. L. del Pozo, M. Batlle, C. Tebé, R. Rigo-Bonnin, C. Muñoz, A. Padullés, F. Tubau, S. Videla, A. Sureda, J. Carratalà
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Trials
Subjects:
Febrile neutropaenia
β-lactam antibiotics
Cefepime
Piperacillin-tazobactam
Meropenem
Extended infusion
Online Access:http://link.springer.com/article/10.1186/s13063-020-04323-0

Internet

http://link.springer.com/article/10.1186/s13063-020-04323-0

Similar Items