Characterization and Catalytic-Site-Analysis of an Aldo-Keto Reductase with Excellent Solvent Tolerance

Characterization and Catalytic-Site-Analysis of an Aldo-Keto Reductase with Excellent Solvent Tolerance

Aldo-keto reductases (AKRs) mediated stereoselective reduction of prochiral carbonyl compounds is an efficient way of preparing single enantiomers of chiral alcohols due to their high chemo-, enantio-, and regio-selectivity. To date, the application of AKRs in the asymmetric synthesis of chiral alco...

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Bibliographic Details
Main Authors: Rui Pei, Weiliang Wu, Yuqian Zhang, Libing Tian, Wei Jiang, Shu-Feng Zhou
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Catalysts
Subjects:
aldo-keto reductase
enzyme assay
organic solvents
chiral alcohol
substrate spectrum
Online Access:https://www.mdpi.com/2073-4344/10/10/1121

Internet

https://www.mdpi.com/2073-4344/10/10/1121

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