Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy?

Androgen receptor in advanced breast cancer: is it useful to predict the efficacy of anti-estrogen therapy?

Abstract Background Androgen receptor (AR) is widely expressed in breast cancer (BC) but its role in estrogen receptor (ER)-positive tumors is still controversial. The AR/ER ratio has been reported to impact prognosis and response to antiestrogen endocrine therapy (ET). Methods We assessed whether A...

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Bibliographic Details
Main Authors: Giuseppe Bronte, Andrea Rocca, Sara Ravaioli, Maurizio Puccetti, Maria Maddalena Tumedei, Emanuela Scarpi, Daniele Andreis, Roberta Maltoni, Samanta Sarti, Lorenzo Cecconetto, Anna Fedeli, Elisabetta Pietri, Valeria De Simone, Silvia Asioli, Dino Amadori, Sara Bravaccini
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Cancer
Subjects:
Androgen receptor
Advanced breast cancer
Anti-estrogen therapy
Endocrine therapy
AR/ER ratio
Online Access:http://link.springer.com/article/10.1186/s12885-018-4239-3

Internet

http://link.springer.com/article/10.1186/s12885-018-4239-3

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