The retinal pigment epithelium in Sorsby Fundus Dystrophy shows increased sensitivity to oxidative stress-induced degeneration

The retinal pigment epithelium in Sorsby Fundus Dystrophy shows increased sensitivity to oxidative stress-induced degeneration

Sorsby Fundus Dystrophy (SFD) is a rare inherited autosomal dominant macular degeneration caused by specific mutations in TIMP3. Patients with SFD present with pathophysiology similar to the more common Age-related Macular Degeneration (AMD) and loss of vision due to both choroidal neovascularizatio...

Full description

Bibliographic Details
Main Authors: Alyson Wolk, Mala Upadhyay, Mariya Ali, Jason Suh, Heidi Stoehr, Vera L. Bonilha, Bela Anand-Apte
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Retinal pigment epithelium
Sorsby Fundus Dystrophy
Age-related macular degeneration
Oxidative stress
Antioxidants
Sodium iodate
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720308867

Internet

http://www.sciencedirect.com/science/article/pii/S2213231720308867

Similar Items