Loss of DNA methylation is related to increased expression of miR-21 and miR-146b in papillary thyroid carcinoma

Loss of DNA methylation is related to increased expression of miR-21 and miR-146b in papillary thyroid carcinoma

Abstract Background DNA methylation in miRNA genes has been reported as a mechanism that may cause dysregulation of mature miRNAs and consequently impact the gene expression. This mechanism is largely unstudied in papillary thyroid carcinomas (PTC). Methods To identify differentially methylated miRN...

Full description

Bibliographic Details
Main Authors: Isabella Maria Dias Payão Ortiz, Mateus Camargo Barros-Filho, Mariana Bisarro dos Reis, Caroline Moraes Beltrami, Fabio Albuquerque Marchi, Hellen Kuasne, Luísa Matos do Canto, Julia Bette Homem de Mello, Cecilie Abildgaard, Clóvis Antônio Lopes Pinto, Luiz Paulo Kowalski, Silvia Regina Rogatto
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
microRNA
miR-146b
miR-21
Papillary thyroid
Carcinoma
Online Access:http://link.springer.com/article/10.1186/s13148-018-0579-8

Internet

http://link.springer.com/article/10.1186/s13148-018-0579-8

Similar Items