A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study

A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the "Treviso Longeva (TRELONG)" study

<p>Abstract</p> <p>Background</p> <p>An attenuation of the insulin-like growth factor 1 (IGF-1) signaling has been associated with elongation of the lifespan in simple metazoan organisms and in rodents. In humans, IGF-1 level has an age-related modulation with a lower c...

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Bibliographic Details
Main Authors: De Angeli Sergio, Gajo Giovanni, Pesaresi Marzia, Vittori Angelica, Polito Letizia, Batelli Sara, Albani Diego, Zanardo Andrea, Gallucci Maurizio, Forloni Gianluigi
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Geriatrics
Online Access:http://www.biomedcentral.com/1471-2318/9/19

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http://www.biomedcentral.com/1471-2318/9/19

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