OppA Escherichia coli mutants have osmodependent resistance to aminoglycoside antibiotics

The oligopeptide permease (OppA) protein was found to be missing in the periplasmic fractions of Escherichia coli kanamycin-resistant mutants selected under high osmotic conditions. The growth behavior of one mutant in media containing kanamycin or the toxic peptide triornithine suggests that OppA a...

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Bibliographic Details
Main Authors: Maria H. Tsuhako, Luis Carlos S. Ferreira, Sérgio Olavo P. da Costa
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 1998-03-01
Series:Genetics and Molecular Biology
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571998000100004