Epithelial-Mesenchymal Transition (EMT) and Regulation of EMT Factors by Steroid Nuclear Receptors in Breast Cancer: A Review and in Silico Investigation

Steroid Nuclear Receptors (SNRs) are transcription factors of the nuclear receptor super-family. Estrogen Receptor (ERα) is the best-studied and has a seminal role in the clinic both as a prognostic marker but also as a predictor of response to anti-estrogenic therapies. Progesterone Receptor (PR) i...

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Bibliographic Details
Main Author: Ioannis A. Voutsadakis
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Journal of Clinical Medicine
Subjects:
PR
AR
GR
MR
Online Access:http://www.mdpi.com/2077-0383/5/1/11