The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells

The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells

Abstract Background Brain endothelial cell-based in vitro models are among the most versatile tools in blood–brain barrier research for testing drug penetration to the central nervous system. Transcytosis of large pharmaceuticals across the brain capillary endothelium involves the complex endo-lysos...

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Bibliographic Details
Main Authors: Andrea E. Toth, Simone S. E. Nielsen, Weronika Tomaka, N. Joan Abbott, Morten S. Nielsen
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Fluids and Barriers of the CNS
Subjects:
bEnd.3 mouse brain endothelial cell line
hCMEC/D3 human brain endothelial cell line
Primary porcine brain endothelial cell
Blood–brain barrier
Endo-lysosomal system
Vesicular transport
Online Access:http://link.springer.com/article/10.1186/s12987-019-0134-9

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http://link.springer.com/article/10.1186/s12987-019-0134-9

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