Increased Exposure of Phosphatidylethanolamine on the Surface of Tumor Vascular Endothelium

We have previously shown that oxidative stress within the tumor microenvironment causes phosphatidylserine (PS) to redistribute from the inner to the outer membrane leaflet of the endothelial cells (EC) creating a highly specific marker for the tumor vasculature. Because the distribution of phospha...

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Bibliographic Details
Main Authors: Jason H. Stafford, Philip E. Thorpe
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800114