ZIP8 Regulates Host Defense through Zinc-Mediated Inhibition of NF-κB

ZIP8 Regulates Host Defense through Zinc-Mediated Inhibition of NF-κB

Activation of the transcription factor NF-κB is essential for innate immune function and requires strict regulation. The micronutrient zinc modulates proper host defense, and zinc deficiency is associated with elevated inflammation and worse outcomes in response to bacterial infection and sepsis. P...

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Bibliographic Details
Main Authors: Ming-Jie Liu, Shengying Bao, Marina Gálvez-Peralta, Charlie J. Pyle, Andrew C. Rudawsky, Ryan E. Pavlovicz, David W. Killilea, Chenglong Li, Daniel W. Nebert, Mark D. Wewers, Daren L. Knoell
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713000168

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http://www.sciencedirect.com/science/article/pii/S2211124713000168

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