Down-Regulation of Telomerase Activity and Activation of Caspase-3 Are Responsible for Tanshinone I-Induced Apoptosis in Monocyte Leukemia Cells in Vitro

Down-Regulation of Telomerase Activity and Activation of Caspase-3 Are Responsible for Tanshinone I-Induced Apoptosis in Monocyte Leukemia Cells in Vitro

Tanshinone I (Tan-I) is a diterpene quinone extracted from the traditional herbal medicine Salvia miltiorrhiza Bunge . Recently, Tan-I has been reported to have anti-tumor effects. In this study, we investigated the growth inhibition and apoptosis inducing effects of Tan-I on three kinds of monocyti...

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Bibliographic Details
Main Authors: Xiao-Dan Liu, Rui-Fang Fan, Yong Zhang, Hong-Zhi Yang, Zhi-Gang Fang, Wei-Bing Guan, Dong-Jun Lin, Ruo-Zhi Xiao, Ren-Wei Huang, He-Qing Huang, Pei-Qing Liu, Jia-Jun Liu
Format: Article
Language:English
Published: MDPI AG 2010-05-01
Series:International Journal of Molecular Sciences
Subjects:
Tanshinone I (Tan-I)
telomerase
survivin
leukemia
Online Access:http://www.mdpi.com/1422-0067/11/6/2267/

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http://www.mdpi.com/1422-0067/11/6/2267/

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