The Mechanisms Involved in Morphine Addiction: An Overview

The Mechanisms Involved in Morphine Addiction: An Overview

Opioid use disorder is classified as a chronic recurrent disease of the central nervous system (CNS) which leads to personality disorders, co-morbidities and premature death. It develops as a result of long-term administration of various abused substances, along with morphine. The pharmacological ac...

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Bibliographic Details
Main Authors: Joanna Listos, Małgorzata Łupina, Sylwia Talarek, Antonina Mazur, Jolanta Orzelska-Górka, Jolanta Kotlińska
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
opioid receptors
adenylate cyclase activity
morphine tolerance and withdrawal signs
mesolimbic system
mitogen-activated kinases (MAP kinases)
β-arrestin
Online Access:https://www.mdpi.com/1422-0067/20/17/4302

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https://www.mdpi.com/1422-0067/20/17/4302

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