Evaluation of Chikungunya diagnostic assays: differences in sensitivity of serology assays in two independent outbreaks.

BACKGROUND: The sensitivity and specificity of two in-house MAC-ELISA assays were tested and compared with the performance of commercially-available CTK lateral flow rapid test and EUROIMMUN IFA assays for the detection of anti-Chikungunya virus (CHIKV) IgM. Each MAC-ELISA assay used a whole virus-b...

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Bibliographic Details
Main Authors: Grace Yap, Kwoon-Yong Pok, Yee-Ling Lai, Hapuarachchige-Chanditha Hapuarachchi, Angela Chow, Yee-Sin Leo, Li-Kiang Tan, Lee-Ching Ng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2907414?pdf=render