Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics

Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics

Huang et al demonstrate that glioblastoma cells upregulate axon guidance molecule Plexin-B2 to gain invasiveness and that Plexin-B2 promotes glioblastoma cell infiltration along axon fiber tracts in intracranial transplant models by modulating cellular biomechanics.

Bibliographic Details
Main Authors: Yong Huang, Rut Tejero, Vivian K. Lee, Concetta Brusco, Theodore Hannah, Taylor B. Bertucci, Chrystian Junqueira Alves, Igor Katsyv, Michael Kluge, Ramsey Foty, Bin Zhang, Caroline C. Friedel, Guohao Dai, Hongyan Zou, Roland H. Friedel
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01667-4

Internet

https://doi.org/10.1038/s42003-021-01667-4

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