Extracellular Vesicles in Acute Leukemia: A Mesmerizing Journey With a Focus on Transferred microRNAs

Extracellular Vesicles in Acute Leukemia: A Mesmerizing Journey With a Focus on Transferred microRNAs

Despite their small size, the membrane-bound particles named extracellular vesicles (EVs) seem to play an enormous role in the pathogenesis of acute leukemia. From oncogenic hematopoietic stem cells (HSCs) to become leukemic cells to alter the architecture of bone marrow (BM) microenvironment, EVs a...

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Bibliographic Details
Main Authors: Mehrdad Izadirad, Zoufang Huang, Farideh Jafari, Amir Ali Hamidieh, Ahmad Gharehbaghian, Yi-Dong Li, Leila Jafari, Zhe-Sheng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
acute myeloblastic leukemia
acute lymphoblastic leukemia
extracellular vesicles
prognosis factor
disease pathogenesis
miRNAs
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.766371/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.766371/full

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