Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in the Hippocampus and PFC

Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in the Hippocampus and PFC

Quercetin is a polyphenol with multiple biological activities, and results of our preliminary study showed that it could shorten the immobility time of mice in the forced swimming test and tail suspending test. The aim of this study was to investigate its effects on the behavioral performance of lip...

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Bibliographic Details
Main Authors: Ke Fang, Hua-Rong Li, Xing-Xing Chen, Xin-Ran Gao, Ling-Ling Huang, An-Qi Du, Chuan Jiang, Hua Li, Jin-Fang Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
quercetin
nesfatin-1
brain derived neurotrophic factor (BDNF)
Copine 6
the triggering receptors expressed on myeloid cells (TREMs)
synapsin-1
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01544/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01544/full

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