Patterns of grey and white matter changes differ between bulbar and limb onset amyotrophic lateral sclerosis

Patterns of grey and white matter changes differ between bulbar and limb onset amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that is characterized by a high heterogeneity in patients’ disease course. Patients with bulbar onset of symptoms (b-ALS) have a poorer prognosis than patients with limb onset (l-ALS). However, neuroimaging correlates of...

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Bibliographic Details
Main Authors: Robert Steinbach, Tino Prell, Nayana Gaur, Annekathrin Roediger, Christian Gaser, Thomas E. Mayer, Otto W. Witte, Julian Grosskreutz
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
Subjects:
Amyotrophic lateral sclerosis
Bulbar-onset
Limb-onset
D50 model
Tract–based spatial statistics
Voxel-based morphometry
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158221001182

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http://www.sciencedirect.com/science/article/pii/S2213158221001182

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