Naja mossambica mossambica Cobra Cardiotoxin Targets Mitochondria to Disrupt Mitochondrial Membrane Structure and Function

Naja mossambica mossambica Cobra Cardiotoxin Targets Mitochondria to Disrupt Mitochondrial Membrane Structure and Function

Cobra venom cardiotoxins (CVCs) can translocate to mitochondria to promote apoptosis by eliciting mitochondrial dysfunction. However, the molecular mechanism(s) by which CVCs are selectively targeted to the mitochondrion to disrupt mitochondrial function remains to be elucidated. By studying cardiot...

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Bibliographic Details
Main Authors: Boris Zhang, Feng Li, Zhengyao Chen, Indira H. Shrivastava, Edward S. Gasanoff, Ruben K. Dagda
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Toxins
Subjects:
cobra cardiotoxin
mitochondria
cardiolipin
mitochondrial dysfunction
non-bilayer membrane structures
Online Access:http://www.mdpi.com/2072-6651/11/3/152

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http://www.mdpi.com/2072-6651/11/3/152

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