A DNA Repair BRCA1 Estrogen Receptor and Targeted Therapy in Breast Cancer
BRCA1 is a key mediator of DNA repair pathways and participates in the maintenance of the genomic integrity of cells. The control of DNA damage repair mechanisms by BRCA1 is of great interest since molecular defects in this pathway may reflect a predictive value in terms of a cell’s se...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-11-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | http://www.mdpi.com/1422-0067/13/11/14898 |