Increased NQO1 but Not c-MET and Survivin Expression in Non-Small Cell Lung Carcinoma with KRAS Mutations

Increased NQO1 but Not c-MET and Survivin Expression in Non-Small Cell Lung Carcinoma with KRAS Mutations

Cigarette smoking is one of the most significant public health issues and the most common environmental cause of preventable cancer deaths worldwide. EGFR (Epidermal Growth Factor Receptor)-targeted therapy has been used in the treatment of LC (lung cancer), mainly caused by the carcinogens in cigar...

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Bibliographic Details
Main Authors: Ahmet Yilmaz, Nehad Mohamed, Kara A. Patterson, Yan Tang, Konstantin Shilo, Miguel A. Villalona-Calero, Michael E. Davis, Xiaoping Zhou, Wendy Frankel, Gregory A. Otterson, Howard D. Beall, Weiqiang Zhao
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Environmental Research and Public Health
Subjects:
lung cancer
non-small cell lung carcinoma
oxidative stress
KRAS
mutation
NQO1
DNA methyl transferase
ERK1/2
c-MET
survivin
Online Access:http://www.mdpi.com/1660-4601/11/9/9491

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http://www.mdpi.com/1660-4601/11/9/9491

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