Intestinal injury and gut permeability in sickle cell disease

Abstract Background Due to recurrent hypoxia-reperfusion injury induced by vaso-occlusive crises (VOC), patients with sickle cell disease (SCD) may have intestinal injury and increased permeability. These may explain the qualitative and quantitative neutrophil abnormalities observed in these patient...

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Bibliographic Details
Main Authors: Dibyendu Dutta, Barbara Methe, Salomon Amar, Alison Morris, Seah H. Lim
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-019-1938-8