Somatic Copy Number Alterations and Associated Genes in Clear-Cell Renal-Cell Carcinoma in Brazilian Patients

Somatic Copy Number Alterations and Associated Genes in Clear-Cell Renal-Cell Carcinoma in Brazilian Patients

Somatic copy number aberrations (CNAs) have been associated with clear-cell renal carcinoma (ccRCC) pathogenesis and are a potential source of new diagnostic, prognostic and therapeutic biomarkers. Recurrent CNAs include loss of chromosome arms 3p, 14q, 9p, and gains of 5q and 8q. Some of these regi...

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Bibliographic Details
Main Authors: Flávia Gonçalves Fernandes, Henrique Cesar Santejo Silveira, João Neif Antonio Júnior, Rosana Antunes da Silveira, Luis Eduardo Zucca, Flavio Mavignier Cárcano, André Octavio Nicolau Sanches, Luciano Neder, Cristovam Scapulatempo-Neto, Sergio Vicente Serrano, Eric Jonasch, Rui Manuel Reis, Adriane Feijó Evangelista
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
copy number aberrations
clear-cell renal-cell carcinoma
bioinformatics
Brazilian population
Online Access:https://www.mdpi.com/1422-0067/22/5/2265

Internet

https://www.mdpi.com/1422-0067/22/5/2265

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