Immununochemical markers of the amyloid cascade in the hippocampus in motor neuron diseases

Immununochemical markers of the amyloid cascade in the hippocampus in motor neuron diseases

Background: Several findings suggest that the amyloid precursor protein (APP) and the amyloid cascade may play a role in motor neuron disease (MND).Objective: Considering that dementia is one of the most frequently non-motor symptoms in ALS and that hippocampus is one of the brain areas with greater...

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Main Authors: Ulises Gomez-Pinedo, Rocio Nur Villar-Quiles, Lucia Galan, Jordi A. Matias-Guiu, Maria Soledad Benito-Martin, Antonio Guerrero-Sola, Teresa Moreno-Ramos, Jorge Matias-Guiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Neurology
Subjects:
Amyotrophic Lateral Sclerosis
Frontotemporal Dementia
amyloid precursor protein
tau protein
TDP-43
Aβ peptide
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00195/full

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http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00195/full

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