11β-hydroxysteroid dehydrogenase type-II activity is affected by grapefruit juice and intense muscular work

11β-hydroxysteroid dehydrogenase type-II activity is affected by grapefruit juice and intense muscular work

ABSTRACT Objective The enzymatic activity of 11β-hydroxysteroid dehydrogenase-2 (11β-HSD2) is key to protecting mineral corticoid receptors from cortisol and has been implicated in blood pressure regulation. Grapefruit juice (GFJ) and acidity are thought to inhibit this enzyme in vitro. This study...

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Bibliographic Details
Main Authors: Christopher Kargl, Mohammad Arshad, Fahad Salman, Regina C. Schurman, Pedro Del Corral
Format: Article
Language:English
Published: Brazilian Society of Endocrinology and Metabolism 2017-09-01
Series:Archives of Endocrinology and Metabolism
Subjects:
Cortisol
cortisone
exertion
stress
citrus flavonoids
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972017000600556&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972017000600556&lng=en&tlng=en

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