Very High Dehydroepiandrosterone Sulfate (DHEAS) in Serum of an Overweight Female Adolescent Without a Tumor

Introduction: An increase of serum dehydroepiandrosterone (DHEA) sulfate (DHEAS) is observed in premature adrenarche and congenital adrenal hyperplasia. Very high DHEAS levels are typical for adrenal tumors. Approximately 74% of DHEAS is hydrolyzed to DHEA by the steroid sulfatase (STS). The reverse...

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Main Authors: Daniel I. Iliev, Regina Braun, Alberto Sánchez-Guijo, Michaela Hartmann, Stefan A. Wudy, Doreen Heckmann, Gernot Bruchelt, Anika Rösner, Gary Grosser, Joachim Geyer, Gerhard Binder
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00240/full