A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes

<p>Abstract</p> <p>Background</p> <p>The mechanism underlying autoimmune diabetes has been difficult to define. There is a strong genetic contribution and numerous studies associate the major histocompatibility complex, especially the class II region, with predispositio...

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Bibliographic Details
Main Authors: Brooks Bernard R, Parry Christian S
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/3/1/42