Heparan sulfate proteoglycan induces the production of NO and TNF-α by murine microglia

<p>Abstract</p> <p>Background</p> <p>A common feature of Alzheimer's disease (AD) pathology is the abundance of activated microglia in neuritic plaques containing amyloid-beta protein (Aβ) and associated molecules including heparan sulfate proteoglycan (HSPG). Besi...

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Bibliographic Details
Main Authors: Bresolin Nereo, Tiriticco Marco, Conti Giancarlo, Clementi Emilio, Scarpini Elio, Meda Lucia, Bussini Simona, Baron Pierluigi
Format: Article
Language:English
Published: BMC 2005-07-01
Series:Immunity & Ageing
Online Access:http://www.immunityageing.com/content/2/1/11