The DNA Binding and Bending Activities of Truncated Tail-less HMGB1 protein are Differentially Affected by Lys-2 and Lys-81 Residues and Their Acetylation
<p>The role of lysines 2 and 81 as target sites for acetylation in full-length HMGB1 and truncated tail-less protein, respectively, has been studied by mutation analysis for the abilities of these proteins to bind and bend DNA. The DNA bending ability of truncated tail-less HMGB1 containing Ly...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Ivyspring International Publisher
2011-01-01
|
Series: | International Journal of Biological Sciences |
Online Access: | http://www.biolsci.org/v07p0691.htm |